Publications scientifiques et académiques

en gras : les chercheurs HDR de LNOx  /  en rouge : les articles phares

2017

Juen L, Brachet-Botineau M, Parmenon C, Bourgeais J, Herault O, Gouilleux F, Viaud-Massuard MC, Prié G. (2017) A new inhibitor targeting signal transducer and activator of transcription 5 (STAT5) signaling in myeloid leukemias. J Med Chem, 60:6119-6136

Desbourdes L, Javary J, Charbonnier T, Ishac N, Bourgeais J, Iltis A, Chomel JC, Turhan A, Guilloton F, Tarte K, Demattei MV, Ducrocq E, Rouleux-Bonnin F, Gyan E, Herault O, Domenech J. (2017) Alteration analysis of bone marrow mesenchymal stromal cells from de novo acute myeloid leukemia patients at diagnosis. Stem Cell Dev, 26:709-722

Ghanem S, Friedbichler K, Boudot C, Bourgeais J, Gouilleux-Gruart V, Regnier V, Herault O, Moriggl R, Gouilleux F (2017) STAT5A/5B-specific expansion and transformation of hematopoietic stem cells. Blood Cancer J, 7:e514

Bourgeais J, Ishac N, Medrzycki M, Brachet-Botineau M, Desbourdes L, Gouilleux-Gruart V, Pecnard E, Rouleux-Bonnin FGyan EDomenech JMazurier F, Moriggl R, Bunting KD, Herault OGouilleux F. (2017) Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses. Oncotarget, 8:41876-41889

Veyrat-Durebex C, Debeissat C, Blasco H, Patin F, Henique H, Emond P, Antar C, Gissot V, Maillot F*, Herault O*. (2017) Phenylalanin plasma concentration is correlated with global decrease of antioxidant genes expression in adult PKU patients. JIMD Rep, mar 15. doi: 10.1007/8904_2017_16 *equal contributors

Gyan E, Raynard B, Durand JP, Lacau Saint Guily J, Gouy S, Movschin ML, Khemissa F, Flori N, Oziel-Taieb S, Bannier Braticevic C, Zeanandin G, Hebert C, Savinelli F, Goldwasser F, Hébuterne X; NutriCancer 2012 Investigator Group. (2017) Malnutrition in patients with cancer. JPEN J Parenter Enteral Nutr 2017 Jan 1:148607116688881. doi: 10.1177/0148607116688881

Aggoune D, Sorel N, Bonnet ML, Goujon JM, Tarte K, Hérault O, Domenech J, Réa D, Legros L, Johnson-Ansa H, Rousselot P, Cayssials E, Guerci-Bresler A, Bennaceur-Griscelli A, Chomel JC, Turhan AG. (2017) Bone marrow mesenchymal stromal cell (MSC) gene profiling in chronic myeloid leukemia (CML) patients at diagnosis and in deep molecular response induced by tyrosine kinase inhibitors (TKIs). Leuk Res, 60:94-102

Chalopin T, Barillot I, Biny JP, Arbion F, Besson M, Santiago-Ribeiro M, Piver E, Herault O, Gyan E, Benboubker L. (2017) Primary solitary plasmacytoma of the liver - successful treatment with fractionated stereotactic radiotherapy (Cyberknife®): a case report. J Med Case Rep, 11:193

Cheloni G, Tanturli M, Tusa I, DeSouza NH, Shan Y, Gozzini A, Mazurier F, Rovida E, Li S, Dello Sbarba P. (2017) Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine. Blood, 130(5):655-666

Nguyen PH, Charbonnier L, Giraud J, Dubus P, Wittkop L, Belleannée G, Collet D, Soubeyran I, Evrard S, Rousseau B, Senant-Dugot N, Mégraud F, Mazurier FVaron C. (2017) Characterization of biomarkers of tumorigenic and chemoresistant cancer cells in human gastric carcinoma. Clin Cancer Res 23:1586-1597

Tout M, Casasnovas O, Meignan M, Lamy T, Morschhauser F, Salles G, Gyan E, Haioun C, Mercier M, Feugier P, Boussetta S, Paintaud G, Ternant D, Cartron G. (2017) Rituximab exposure is influenced by baseline metabolic tumor volume and predicts outcome of DLBCL patients: a LYSA study. Blood, 129:2616-2623

Poulain L, Sujobert P, Zylbersztejn F, Barreau S, Stuani L, Lambert M, Palama T, Chesnais V, Birsen R, Vergez F, Farge T, Chenevier-Gobeaux C, Fraisse M, Bouillaud F, Debeissat C, Herault O, Recher C, Lacombe C, Fontenay M, Mayeux P, Maciel T, Portais JC, Sarry JE, Tamburini J, Bouscary D, Chapuis N. (2017) High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells. Leukemia, 31:2326-2335

Freund P, Kerenyi M, Hager M, Wagner T, Wingelhofer B, Thi Thanh Pham H, Elabd M, Han X, Valent P, Gouilleux F, Sexl V, Krämer O, Groner B, Moriggl R. (2017) O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies. Leukemia 31:2132-2142

Cahu X, Carré M, Recher C, Pigneux A, Hunault-Berger M, Vey N, Chevallier P, Delaunay J, Gyan E, Lioure B, Bonmati C, Himberlin C, Hichri Y, Guillerm G, Bouscary D, Larosa F, Ojeda-Uribe M, Bernard M, Béné MC, Ifrah N, Cahn JY. (2017) Impact of body-surface area on patients' outcome in younger adults with acute myeloid leukemia. Eur J Haematol, 98:443-449

Damaj G, Cornillon J, Bouabdallah K, Gressin R, Vigouroux S, Gastinne T, Ranchon F, Ghésquières H, Salles G, Yakoub-Agha I, Gyan E. (2017) Carmustine replacement in intensive chemotherapy preceding reinjection of autologous HSCs in Hodgkin and non-Hodgkin lymphoma: a review. Bone Marrow Transplant, 52:941-949

Gauthier J, Castagna L, Garnier F, Guillaume T, Socié G, Maury S, Maillard N, Tabrizi R, Marchand T, Malfuson J, Gac A, Gyan E, Mercier M, Béguin Y, Delage J, Turlure P, Marçais A, Nguyen S, Dulery R, Bay J, Huynh A, Daguindau E, Cornillon J, Régny C, Michallet M, Peffault de Latour R, Yakoub-Agha I, Blaise D. Reduced-intensity and non-myeloablative allogeneic stem cell transplantation from alternative HLA-mismatched donors for Hodgkin lymphoma: a study by the French Society of Bone Marrow Transplantation and Cellular Therapy. Bone Marrow Transplant, 52:689-696

Tchernonog E, Faurie P, Coppo P, Monjanel H, Bonnet A, Algarte Génin M, Mercier M, Dupuis J, Bijou F, Herbaux C, Delmer A, Fabiani B, Besson C, Le Gouill S, Gyan E, Laurent C, Ghesquieres H, Cartron G. (2017) Clinical characteristics and prognostic factors of plasmablastic lymphoma patients: analysis of 135 patients from the Lysa group. Ann Oncol, 28:843-848

Shi Q, Flowers CR, Hiddemann W, Marcus R, Herold M, Hagenbeek A, Kimby E, Hochster H, Vitolo U, Peterson BA, Gyan E, Ghielmini M, Nielsen T, De Bedout S, Fu T, Valente N, Fowler NH, Hoster E, Ladetto M, Morschhauser F, Zucca E, Salles G, Sargent DJ. Thirty-month complete response as a surrogate end point in first-line follicular lymphoma therapy: an individual patient-level analysis of multiple randomized trials. J Clin Oncol, 2016 Dec 28:JCO2016708651

Tabouret E, Houillier C, Martin-Duverneuil N, Blonski M, Soussain C, Ghesquières H, Houot R, Larrieu D, Soubeyran P, Gressin R, Gyan E, Chinot O, Taillandier L, Choquet S, Alentorn A, Leclercq D, Omuro A, Tanguy ML, Hoang-Xuan K. (2017) Patterns of response and relapse in primary CNS lymphomas after first-line chemotherapy: imaging analysis of the ANOCEF-GOELAMS prospective randomized trial. Neuro Oncol, 19:422-429

Aspeslagh S, Stein M, Bahleda R, Hollebecque A, Salles G, Gyan E, Fudio S, Extremera S, Alfaro V, Soto-Matos A, Soria JC. (2017) Phase I dose-escalation study of plitidepsin in combination with sorafenib or gemcitabine in patients with refractory solid tumors or lymphomas. Anticancer Drugs, 28:341-349

Kraeber-Bodere F, Pallardy A, Maisonneuve H, Campion L, Moreau A, Soubeyran I, Le Gouill S, Tournilhac O, Daguindau E, Jardel H, Morineau N, Bouabdallah K, Gyan E, Moles MP, Gressin R, Berthou C, Sadot S, Moreau P, Deau B, Bodet-Milin C, Cazeau AL, Garin E, Salaun PY, Vuillez JP, Gouilleux-Gruart V, Barbet J, Wegener WA, Goldenberg DM, Lamy T, Soubeyran P. (2017) Consolidation anti-CD22 fractionated radioimmunotherapy with 90Y-epratuzumab tetraxetan following R-CHOP in elderly patients with diffuse large B-cell lymphoma: a prospective, single group, phase 2 trial. Lancet Haematol, 4:e35-e45

Raynard B, Hébuterne X, Goldwasser F, Ait Hssain A, Dubray Longeras P, Barthélémy P, Rosso E, Phoutthasang V, Bories C, Digue L, Laharie D, Desport JC, Falkowski S, Lacau Saint Guily J, Gyan E. (2017) Crossed perceptions about malnutrition in patients and their doctors in oncology. Bull Cancer, 2017 Nov 8. pii: S0007-4551(17)30265-5. d10.1016/j.bulcan.2017.09.014

Sébert M, Komrokji RS, Sekeres MA, Prebet T, Cluzeau T, Santini V, Gyan E, Sanna A, Ali NH, Hobson S, Eclache V, List A, Fenaux P, Adès L. (2017) Impact of baseline cytogenetic findings and cytogenetic response on outcome of high-risk myelodysplastic syndromes and low blast count AML treated with azacitidine. Leuk Res, 63:72-77

Lamy T, Damaj G, Soubeyran P, Gyan E, Cartron G, Bouabdallah K, Gressin R, Cornillon J, Banos A, Le Du K, Benchalal M, Moles MP, Le Gouill S, Fleury J, Godmer P, Maisonneuve H, Deconinck E, Houot R, Laribi K, Marolleau JP, Tournilhac O, Branger B, Devillers A, Vuilliez JP, Fest T, Colombat P, Costes V, Szablewski V, Béné MC, Delwail V. (2017) R-CHOP 14 with or without radiotherapy in non-bulky limited-stage diffuse large B-cell lymphoma (DLBCL). Blood. 2017 Oct 23. pii: blood-2017-07-793984. doi: 10.1182/blood-2017-07-793984.

Fargier E, Ranchon F, Huot L, Guerre P, Safar V, Dony A, Hequet N, Bachy E, Savouroux S, Fronteau C, Tomaré P, Tournamille JF, Schwiertz V, Vantard N, Le Gouill S, Gyan E, Salles G, Rioufol C. (2017) SMABcare study: subcutaneous monoclonal antibody in cancer care: cost-consequence analysis of subcutaneous rituximab in patients with follicular lymphoma. Ann Hematol. 2017 Oct 10. doi: 10.1007/s00277-017-3147-y.

Lacau St Guily J, Bouvard É, Raynard B, Goldwasser F, Maget B, Prevost A, Seguy D, Romano O, Narciso B, Couet C, Balon JM, Vansteene D, Salas S, Grandval P, Gyan E, Hebuterne X. (2017) NutriCancer: A French observational multicentre cross-sectional study of malnutrition in elderly patients with cancer. J Geriatr Oncol. 2017 Sep 6. pii: S1879-4068(17)30150-9. doi: 10.1016/j.jgo.2017.08.003.


2016

Bourgeais J*, Bustany S*, Tchakarska G, Body S, Herault OGouilleux F, Sola B. (2016) Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells. Oncotarget, 7:45214-45224 *equal contributors

Bire S, Ishac N, Rouleux-Bonnin F. (2016) In vitro synthesis, delivery, and bioavailability of exogenous mRNA in gene transfer mediated by PiggyBac transposition. Methods Mol Biol 1428:187-217

Bastie C, Rouleux-Bonnin F. DNA elements tetris: a Strategy for gene correction.  In: Modern Tools for Genetic Engineering. Edited by Michael S.D. Kormann. InTech, Rijeka, Croatia, 2016 http://dx.doi.org/10.5772/62382

Domenech J. What are MSCs? Origin and discovery of mesenchymal stromal cells (MSCs). In: Mesenchymal stromal cells as tumor stromal modulators. Edited by Garcia & Bolontrade. Academic Press/Elsevier Science, Amsterdam, Pays-Bas, 2016, pages 1-37

Deynoux M, Sunter N, Hérault O, Mazurier F. (2016) Hypoxia and hypoxia-inducible factors in leukemia's. Front Oncol 6:41

Gyan E, Andrieu V, Sanna A, Caille A, Schemenau J, Sudaka I, Siguret V, Malet M, Park S, Bordessoule D, Mairesse J, Gelsi-Boyer V, Cheze S, Beyne-Rauzy O, Sébert M, Sapena R, Zerazhi H, Legros L, Guerci-Bresler A, Amé SN, Germing U, Santini V, Salvi F, Gioia D, Lunghi M, Dreyfus F, Fenaux P, Groupe Francophone des Myélodysplasies, Fondazione Italiana per le Sindromi Mielodisplastiche (FISMonlus), and Düsseldorf MDS Registry. (2016) Myelodysplastic syndromes with single neutropenia or thrombocytopenia are rarely refractory cytopenias with unilineage dysplasia by World Health Organization 2008 criteria and have favourable prognosis. Br J Haematol 175:975-979

Zhang Y, Dépond M, He L, Foudi A, Kwarteng E, Lauret E, Plo I, Desterke C, Dessen P, Fujii N, Opolon P, Herault O, Solary E, Vainchenker W, Joulin V, Louache F, M Wittner M. (2016) CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress. Sci Rep 6:37827

Themmans M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracianno LM, Han X, Kenner L, Wagner K, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R. (2016) Hepatic deletion of Janus Kinase 2 counteracts oxidative stress in mice. Sci Rep, 6:34719

Brachet G, Bruno C, Boulay D, Tournamille JF, Gyan E, Viaud-Massuard MC, Respaud R. (2016) An ion-pairing, reversed-phase liquid chromatography method to assess the cross-contamination of cancer chemotherapy infusions prepared in a dual-operator aseptic isolator. Drug Test Anal Drug Test Anal, 8:985-90

Lioger B, Ferreira-Maldent N, Cottier JP, Debiais S, Gyan E, Maillot F. (2016) Rituximab for Sjögren syndrome-associated type II mixed cryoglobulinemic cerebral vasculitis. Neurol Neuroimmunol Neuroinflamm, 3:e253

Reboursiere E, Le Bras F, Herbaux C, Gyan E, Clavert A, Morschhauser F, Malak S, Sibon D, Broussais F, Braun T, Fornecker LM, Garidi R, Tricot S, Houot R, Joly B, Abarah W, Choufi B, Pham AD, Gac AC, Fruchart C, Marin E, Safar V, Parcelier A, Maisonneuve H, Bachy E, Cartron G, Jaccard A, Tournilhac O, Rossi C, Schirmer L, Martignoles JA, Gaulard P, Tilly H, Damaj G, Lymphoma Study Association Lysa Centers. (2016) Bendamustine for the treatment of relapsed or refractory peripheral T cell lymphomas: A French retrospective multicenter study. Oncotarget, 7:85573-85583

Tixier F, Ranchon F, Iltis A, Vantard N, Schwiertz V, Bachy E, Bouafia-Sauvy F, Sarkozy C, Tournamille JF, Gyan E, Salles G, Rioufol C. (2016) Comparative toxicities of 3 platinum-containing chemotherapy regimens in relapsed/refractory lymphoma patients. Hematol Oncol, 2016 Jul 5. doi: 10.1002/hon.2328

Chandesris MO, Damaj G, Canioni D, Brouzes C, Lhermitte L, Hanssens K, Frenzel L, Cherquaoui Z, Durieu I, Durupt S, Gyan E, Beyne-Rauzy O, Launay D, Faure C, Hamidou M, Besnard S, Diouf M, Schiffmann A, Niault M, Jeandel PY, Ranta D, Gressin R, Chantepie S, Barete S, Dubreuil P, Bourget P, Lortholary O, Hermine O; CEREMAST Study Group. (2016) Midostaurin in advanced systemic mastocytosis. N Engl J Med, 374:2605-2607

Murhez K, Benz-de Bretagne I, Nadal-Desbarats L, Blasco H, Gyan E, Choquet S, Montigny F, Emond P, Barin-Le Guellec C. (2016) Endogenous metabolites that are substrates of Organic Anion Transporter's (OATs) predict methotrexate clearance. Pharmacol Res. 2016 May 19. pii: S1043-6618(16)30469-8

Chaumier F, Gyan E, Vallet N, Hérault B, Mallet D.(2016) Acute Myeloblastic Leukemia in the Elderly: How Could Palliative Care Teams and Hematologists Better Work Together? J Palliat Med, 9:906-907

Langner-Lemercier S, Houillier C, Soussain C, Ghesquières H, Chinot O, Taillandier L, Soubeyran P, Lamy T, Morschhauser F, Benouaich-Amiel A, Ahle G, Moles-Moreau MP, Moluçon-Chabrot C, Bourquard P, Damaj G, Jardin F, Larrieu D, Gyan E, Gressin R, Jaccard A, Choquet S, Brion A, Casasnovas O, Colin P, Reman O, Tempescul A, Marolleau JP, Fabbro M, Naudet F, Hoang-Xuan K, Houot R. (2016) Primary CNS lymphoma at first relapse/progression: characteristics, management, and outcome of 256 patients from the French LOC network. Neuro Oncol, 18:1297-1303

Gac AC, Azar N, Daguindau E, Cartron G, Fornecker LM, Gyan E, Broussais-Guillaumot F, Garidi R, Choufi B, Chantepie SP, Béné MC, Guiéze R, Bijou F, Gressin R, Amorim S, Damaj G. (2016) Does bendamustine impact the mobilization of peripheral blood stem cells? A multicenter retrospective study of 23 cases. Leuk Lymphoma, 57:1149-1153

Desoubeaux G, Cabanne É, Franck-Martel C, Gombert M, Gyan E, Lissandre S, Renaud M, Monjanel H, Dartigeas C, Bailly É, Van Langendonck N, Chandenier J. (2016) Pulmonary toxoplasmosis in immunocompromised patients with interstitial pneumonia: a single-centre prospective study assessing PCR-based diagnosis. J Clin Pathol, 69:726-730

Doyen H, Monjanel H, Regina S, Magnant J, Arbion F, Lissandre S, Gyan E, Le Lez ML. (2016) A case of chorioretinopathy as first manifestation of Hodgkin's lymphoma. Retin Cases Brief Rep, 10:239-243

Toma A, Kosmider O, Chevret S, Delaunay J, Stamatoullas A, Rose C, Beyne-Rauzy O, Banos A, Guerci-Bresler A, Wickenhauser S, Caillot D, Laribi K, De Renzis B, Bordessoule D, Gardin C, Slama B, Sanhes L, Gruson B, Makhoul PC, Chouffi B, Salanoubat C, Benramdane R, Legros L, Wattel E, Tertian G, Bouabdallah K, Guilhot F, Taksin AL, Cheze S, Maloum K, Nimuboma S, Soussain C, Isnard F, Gyan E, Petit R, Lejeune J, Sardnal V, Renneville A, Preudhomme C, Fontenay M, Fenaux P, Dreyfus F. (2016) Lenalidomide with or without erythropoietin in transfusion dependent erythropoiesis-stimulating agent-refractory lower risk MDS without 5q deletion. Leukemia, 30:897-905

2015

Omuro A, Chinot O, Taillandier L, Ghesquieres H, Soussain C, Delwail V, Lamy T, Gressin R, Choquet S, Soubeyran P, Huchet A, Benouaich-Amiel A, Lebouvier-Sadot S, Gyan E, Touitou V, Barrié M, Del Rio MS, Gonzalez-Aguilar A, Houillier C, Delgadillo D, Lacomblez L, Tanguy ML, Hoang-Xuan K. (2015) Methotrexate and temozolomide versus methotrexate, procarbazine, vincristine, and cytarabine for primary CNS lymphoma in an elderly population: an intergroup ANOCEF-GOELAMS randomised phase 2 trial. Lancet Haematol 2:e251-9 (IF2015=4,889)

Hosseini M, Mahfouf W, Serrano-Sanchez M, Raad H, Harfouche G, Bonneu M, Claverol S, Mazurier F, Rossignol R, Taieb A, Rezvani HR. (2014) Premature Skin Aging Features Rescued by Inhibition of NADPH Oxidase Activity in XPC-Deficient Mice. J Invest Dermatol, 135:1108-1118 (IF2015=6,915)

Carvalhosa AB, Aouba A, Damaj G, Canioni D, Brouzes C, Gyan E, Durupt S, Durieu I, Cathebras P, Costédoat-Chalumeau N, Launay D, Pilmis B, Barete S, Frenzel L, Lortholary O, Hermine O, Hermans C, Chandesris MO. (2015) A French national survey on clotting disorders in mastocytosis. Medicine (Baltimore) 94:e1414 (IF2015=2,133)

Lazarovici J, Dartigues P, Brice P, Obéric L, Gaillard I, Hunault-Berger M, Broussais-Guillaumot F, Gyan E, Bologna S, Nicolas-Virelizier E, Touati M, Casasnovas O, Delarue R, Orsini-Piocelle F, Stamatoullas A, Gabarre J, Fornecker LM, Gastinne T, Peyrade F, Roland V, Bachy E, André M, Mounier N, Fermé C. Nodular lymphocyte predominant Hodgkin lymphoma: a Lymphoma Study Association retrospective study. Haematologica, 100:1579-86 (IF2015=6,671)

Gatault P, Brachet G, Ternant D, Degenne D, Récipon G, Barbet C, Gyan E, Gouilleux-Gruart V, Bordes C, Farrell A, Halimi JM, Watier H. (2015) Therapeutic drug monitoring of eculizumab: rationale for an individualized dosing schedule. MAbs, 7:1205-1211 (IF2015=4,161)

Gautier J, Allard-Vannier E, Burlaud-Gaillard J, Domenech J, Chourpa I. (2015) Efficacy and hemotoxicity of stealth doxorubicin-loaded magnetic nanovectors on breast. cancer xenografts. J Biomed Nanotechnol, 11:177-189 (IF2015=3,929)

Barete S, Lortholary O, Damaj G, Hirsch I, Chandesris MO, Elie C, Hamidou M, Durieu I, Suarez F, Grosbois B, Limal N, Gyan E, Larroche C, Guillet G, Kahn JE, Casassus P, Amazzough K, Coignard-Biehler H, Georgin-Lavialle S, Lhermitte L, Fraitag S, Canioni D, Dubreuil P, Hermine O. (2015) Long-term efficacy and safety of cladribine (2-CdA) in adult patients with mastocytosis. Blood 126:1009-1016 (IF2015=11,847)


Ramos F, Thépot S, Pleyer L, Maurillo L, Itzykson R, Bargay J, Stauder R, Venditti A, Seegers V, Martínez-Robles V, Burgstaller S, Récher C, Debén G, Gaidano G, Gardin C, Musto P, Greil R, Sánchez-Guijo F, Fenaux P; European ALMA Investigators. (2015) Azacitidine frontline therapy for unfit acute myeloid leukemia patients: clinical use and outcome prediction. Leuk Res, 39:296-306 (IF2015=2,606)


Michot JM, Canioni D, Driss H, Alric L, Cacoub P, Suarez F, Sibon D, Thieblemont C, Dupuis J, Terrier B, Feray C, Tilly H, Pol S, Leblond V, Settegrana C, Rabiega P, Barthe Y, Hendel-Chavez H, Nguyen-Khac F, Merle-Béral H, Berger F, Molina T, Charlotte F, Carrat F, Davi F, Hermine O, Besson C; ANRS HC-13 Lympho-C Study Group. (2015) Antiviral therapy is associated with a better survival in patients with hepatitis C virus and B-cell non-Hodgkin lymphomas, ANRS HC-13 lympho-C study. Am J Hematol, 90:197-203 (IF2015=5,000)

Lafia E, Anani L, Glitho S, Bankole C, Fachinan H, Py JY, Domenech J, Martenot B, Colombat P, Chobli M, Zohoun I. (2015) North-South cooperation on transfusion and hematology teaching: A Benin experience. Transfus Clin Biol, 22:80-82 (IF2015=0,561)

Guièze R, Gyan E, Tournilhac O, Halty C, Veyrat-Masson R, Akil S, Berger M, Hérault O, Callanan M, Bay JO. (2015) Docosahexaenoic acid induces apoptosis in primary chronic lymphocytic leukemia cells. Hematol Rep 7:6043

Gyan E, Dreyfus F, Fenaux P. (2015) Refractory thrombocytopenia and neutropenia: a diagnostic challenge. Mediterr J Hematol Infect Dis. 7(1):e2015018

2014

Berger A, Hoelbl-Kovacic A, Bourgeais J, Hoefling L, Warsch W, Grundschober E, Uras I, Menzl I, Putz E, Hoermann G, Schuster C, Fajmann S, Leitner E, Kubicek S, Moriggl R, Gouilleux F, Sexl V. (2014) PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis. Leukemia 28:629-641 (IF2014=10,431)

Chaigne B, Dartigeas C, Benboubker L, Chaumier F, Ertault M, Lissandre S, Stacoffe M, Maillot F, Blasco H, Vourc'h P, Colombat P, Gyan E. (2014) Could a citrus keep the hematologist away? Br J Haematol, 166:298-300 (IF2014=4,971)

Guilleminault L, Azzopardi N, Arnoult C, Sobilo J, Hervé V, Montharu J, Guillon A, Andres C, Herault O, Le Pape A, Diot P, Lemarié E, Paintaud G, Gouilleux-Gruart V, Heuzé-Vourc'h N. (2014) Fate of inhaled monoclonal antibodies after the deposition of aerosolized particles in the respiratory system. J Control Release, 196C:344-354 (IF2014=7,705)

Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y. (2014) IL-2 phosphorylates STAT5 to drive IFN-γ production and activation of human dendritic cells. J Immunol, 192:5660-5670 (IF2014=4,922)

Le Nail LR, Stanovici J, Fournier J, Splingard M, Domenech J, Rosset P. (2014) Percutaneous grafting with bone marrow autologous concentrate for open tibia fractures: analysis of forty three cases and literature review. Int Orthop 38:1845-1853 (IF2014=2,110)

Desoubeaux G, Franck-Martel C, Bailly E, Le Brun C, Gyan E, Goudeau A, Chandenier J, Lanotte P. (2014) Prospective assessment of FilmArray® technology for the rapid identification of yeast isolated from blood cultures. J Microbiol Meth, 106C:119-122 (IF2014=2,026)

Goldberg SL, Fenaux P, Craig MD, Gyan E, Lister J, Kassis J, Pigneux A, Schiller GJ, Jung J, Jane Leonard E, Fingert H, Westervelt P. (2014) An exploratory phase 2 study of investigational Aurora A kinase inhibitor alisertib (MLN8237) in acute myelogenous leukemia and myelodysplastic syndromes. Leuk Res Rep 3:58-61

Rossille D, Gressier M, Damotte D, Maucort-Boulch D, Pangault C, Semana G, Le Gouill S, Haioun C, Tarte K, Lamy T, Milpied N, Fest T; for the Groupe Ouest-Est des Leucémies et Autres Maladies du Sang. (2014) High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: results from a French multicenter clinical trial. Leukemia 28:2367-2375 (IF2014=10,431)

Cornet E, Tomowiak C, Tanguy-Schmidt A, Lepretre S, Dupuis J, Feugier P, Devidas A, Mariette C, Leblond V, Thiéblemont C, Validire-Charpy P, Sutton L, Gyan E, Eisenmann JC, Cony-Makhoul P, Ysebaert L, Troussard X; on the behalf of the Société Française d'Hématologie. (2014) Long-term follow-up and second malignancies in 487 patients with hairy cell leukaemia. Br J Haematol, 166:390-400 (IF2014=4,971)

Damaj G, Joris M, Chandesris O, Hanssens K, Soucie E, Canioni D, Kolb B, Durieu I, Gyan E, Livideanu C, Chèze S, Diouf M, Garidi R, Georgin-Lavialle S, Asnafi V, Lhermitte L, Lavigne C, Launay D, Arock M, Lortholary O, Dubreuil P, Hermine O. (2014) ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases. PLoS One, 9:e85362 (IF2014=3,234)

Touzeau C, Leux C, Bouabdallah R, Roussel M, Delarue R, Bouabdallah K, Thieblemont C, Cacheux V, Cartron G, Compain L, Gyan E, Morschhauser F, Casasnovas O, Moles MP, Michallet AS, Gressin R, Damaj G, Rose C, Sirvent A, Hermine O, Mohty M, Milpied N, Le Gouill S. (2014) Autologous stem cell transplantation in mantle cell lymphoma: a report from the SFGM-TC. Ann Hematol, 93:233-242 (IF2014=2,634)

Benz-de Bretagne I, Zahr N, Le Gouge A, Hulot JS, Houillier C, Hoang-Xuan K, Gyan E, Lissandre S, Choquet S, Le Guellec C. (2014) Urinary coproporphyrin I/(I+III) ratio as a surrogate for MRP2 or other transporter activities involved in methotrexate clearance. Br J Clin Pharmacol, 78:329-342 (IF2014=3,878)


Awan FT, Hillmen P, Hellmann A, Robak T, Hughes SG, Trone D, Shannon M, Flinn IW, Byrd JC; LUCID trial investigators. (2014) A randomized, open-label, multicentre, phase 2/3 study to evaluate the safety and efficacy of lumiliximab in combination with fludarabine, cyclophosphamide and rituximab versus fludarabine, cyclophosphamide and rituximab alone in subjects with relapsed chronic lymphocytic leukaemia. Br J Haematol, 167:466-77 (IF2014=4,971)


Kofman T, Zhang SY, Copie-Bergman C, Moktefi A, Raimbourg Q, Francois H, Karras A, Plaisier E, Painchart B, Favre G, Bertrand D, Gyan E, Souid M, Roos-Weil D, Desvaux D, Grimbert P, Haioun C, Lang P, Sahali D, Audard V. (2014) Minimal change nephrotic syndrome associated with non-Hodgkin lymphoid disorders: a retrospective study of 18 cases. Medicine, 93:350-358 (IF2014=5,723)

2013

Rouault-Pierre K, Lopez-Onieva L, Foster K, Anjos-Afonso F, Lamrissi-Garcia I, Serrano-Sanchez M, Mitter R, Ivanovic Z, de Verneuil H, Gribben J, Taussig D, Rezvani HR, Bonnet D*, Mazurier F*. (2013) HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress. Cell Stem Cell, 13:549-563 *equal contributors (IF 2013=25,911) 

Bire S, Ley D, Casteret S, Mermod N, Bigot Y, Rouleux-Bonnin F. (2013) Optimization of the piggyBac transposon using mRNA and insulators: Toward a more reliable gene delivery system. PLoS One, 8:e82559 (IF2013=3,534)

Bire S, Gosset D, Jégot G, Midoux P, Pichon C, Rouleux-Bonnin F. (2013) Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition. BMC Biotechnol, 13:75 (IF2013=2,592)

Bourgeais J, Gouilleux-Gruart V, Gouilleux F. (2013) Oxidative metabolism in Cancer: a STAT affair ? JAK-STAT, 2:e25764 1-8 (revue)

Vignon C, Debeissat C, Georget MT, Bouscary D, Gyan E, Rosset P, Herault O.  (2013) Flow cytometric quantification of all phases of the cell cycle and apoptosis in a two-color fluorescence plot. PLoS One, 8:e68425 1-8 (IF2013=3,534)

Bire S, Rouleux-Bonnin F. (2013) Transgene site-specific integration: problems and solutions. Top Curr Genet. 2013,  23:3-39 (revue)

Francia T, Hanna J, Herault O. (2013) Contribution of the polyvalent medical laboratory in the exploration of leukocytosisImmuno-Anal Biol Spe, 28:216-222 (IF2013=0,112)

Ley D, Harraghy N, Le Fourn V, Bire S, Girod PA, Regamey A, Rouleux-Bonnin F, Bigot Y, Mermod N. (2013) MAR elements and transposons for improved transgene integration and expression. PLoS One, 8:e62784 (IF2013=3,534)

Radesi-Sarghi S, Arbion F, Dartigeas C, Delain M, Benboubker L, Herault O, Colombat P, Gyan E. (2013) Interferon alpha with or without rituximab achieves a high response rate and durable responses in relapsed FL: 17 years' experience in a single centre. Ann Hematol. 2013 Nov 14 (IF2013=2,396)

Quéré P, Pierre J, Hoang MD, Esnault E, Domenech J, Sibille P, Dimier-Poisson I. (2013) Presence of dendritic cells in chicken spleen cell preparations and their functional interaction with the parasite Toxoplasma gondii. Vet Immunol Immunopathol, 153:57-69 (IF 2013=1,748)

Respaud R, Quenuma L,  Plichon C, Tournamille JF, Gyan E, Antier D, Viaud-Massuard MC. (2013) A stability-indicating, ion-pairing, reversed-phase liquid chromatography method for studies of daunorubicin degradation in i.v. infusion fluids. J Pharm Biomed Anal, 83:164–170 (IF2013=2,829)

Gyan E, Damotte D, Courby S, Sénécal D, Quittet P, Schmidt A , Banos A, Le Gouill S, Lamy T, Fontan J, Maisonneuve H, Alexis A, Dreyfus F, Tournilhac O, Laribi K, Solal-Céligny P, Arakelyan N, Cartron G, Gressin R, on behalf of the GOELAMS study. (2013) High response rate and acceptable toxicity of a combination of rituximab, vinorelbine, 4 ifosfamide, mitoxantrone and prednisone for the treatment of diffuse large B-cell lymphoma in first 5 relapse: results of the R-NIMP GOELAMS study. Br J Haematol, 162:240-249 (IF2013=4,959)

Ianotto JC, Boyer-Perrard F, Gyan E, Laribi K, Cony-Makhoul P, Demory JL, De Renzis B, Dosquet C, Rey J, Roy L, Dupriez B, Knoops L, Legros L, Malou M, Hutin P, Ranta D, Schoenwald M, Andreoli A, Abgrall JF, Kiladjian JJ. (2013) Efficacy and safety of pegylated-interferon α-2a in myelofibrosis: a study by the FIM and GEM French cooperative groups. Br J Haematol, 162:783-791 (IF2013=4,959)

Salles GA, Morschhauser F, Solal-Céligny P, Thieblemont C, Lamy T, Tilly H, Gyan E, Lei G, Wenger M, Wassner-Fritsch E, Cartron G. (2013) Obinutuzumab (GA101) in patients with relapsed/refractory indolent non-Hodgkin lymphoma: results from the phase II GAUGUIN study. J Clin Oncol, 31:2920-2926 (IF2013=17,960)

Pascal L, Beyne-Rauzy O, Brechignac S, Marechaux S, Vassilieff D, Ernst O, Berthon C, Gyan E, Gourin MP, Dreyfus F, Fenaux P, Rose C. (2013) Cardiac iron overload assessed by T2* magnetic resonance imaging and cardiac function in regularly transfused myelodysplastic syndrome patients. Br J Haematol, 162:413-415 (IF2013=4,959)

Trebouet A, Marchand T, Lemal R, Gyan E, Broussais-Guillaumot F, Guillermin Y, Monjanel H, Salles G, Le Gouill S, Godmer P, Fruchart C, Damaj G, Feugier P, Thieblemont C, Maynadié M, Monnereau A, Troussard X, Rossille D, Lamy T, Houot R. (2013) Lymphoma occurring in patients over 90 years of age: characteristics, outcomes, and prognostic factors. A retrospective analysis of 234 cases from the LYSA. Ann Oncol, 24:2612-2618 (IF2013=6,578)

Pessis R, Bahé L, Gyan E, Zakine G, Atlan M. (2013) Occult Primary MALT lymphoma of the breast diagnosed and treated by reduction mammaplasty. An exceptional case report and review of the literature. Ann Chir Plast Esthet, 58:684-687

Ghesquières H, Stamatoullas A, Casasnovas O, Morschhauser F, Gyan E, Gabarre J, Malphettes M, Clément L, Ferlay C, Brice P. Clinical experience of bendamustine in relapsed or refractory Hodgkin lymphoma: a retrospective analysis of the French compassionate use program in 28 patients. Leuk Lymphoma, 54:2399-2404 (IF2013=2,605)

Khellaf M, Vialard JF, Hamidou M, Cheze S, Roudot-Thoraval F, Lefrere F, Fain O, Audia S, Abgrall JF, Michot JM, Dauriac C, Lefort S, Gyan E, Niault M, Durand JM, Languille L, Boutboul D, Bierling P, Michel M, Godeau B. A retrospective pilot evaluation of switching thrombopoietic receptor-agonists in immune thrombocytopenia. Haematologica, 98:881-887 (IF2013=5,868)

Kelaidi C, Beyne-Rauzy O, Braun T, Sapena R, Cougoul P, Adès L, Pillard F, Lambert C, Charniot JC, Guerci A, Choufi B, Stamatoullas A, Slama B, De Renzis B, Ame S, Damaj G, Boyer F, Chaury MP, Legros L, Cheze S, Testu A, Gyan E, Béné MC, Rose C, Dreyfus F, Fenaux P. (2013) High response rate and improved exercise capacity and quality of life with a new regimen of darbepoetin alfa with or without filgrastim in lower-risk myelodysplastic syndromes: a phase II study by the GFM. Ann Hematol, 92:621-631 (IF 2013=2,396)

Damaj G, Gressin R, Bouabdallah K, Cartron G, Choufi B, Gyan E, Banos A, Jaccard A, Park S, Tournilhac O, Schiano-de Collela JM, Voillat L, Joly B, Le Gouill S, Saad A, Cony-Makhoul P, Vilque JP, Sanhes L, Schmidt-Tanguy A, Bubenheim M, Houot R, Diouf M, Marolleau JP, Béné MC, Martin A, Lamy T. (2013) Results From a Prospective, Open-Label, Phase II Trial of Bendamustine in Refractory or Relapsed T-Cell Lymphomas: The BENTLY Trial. J Clin Oncol, 31:104-110 (IF 2013=17,960)

2012

Herault O, Hope KJ, Deneault E, Mayotte N, Chagraoui J, Wilhelm BT, Cellot S, Sauvageau M, Andrade-Navarro M, Hébert J, Sauvageau G. A role for GPx3 in activity of normal and leukemia stem cells. (2012) J Exp Med, 209:895-901 (IF2012=13,214)

Ponte AL, Ribeiro-Fleury T, Chabot V, Gouilleux F, Langonné A, Herault O, Charbord P, Domenech J. G-CSF stimulation of bone marrow mesenchymal stromal cells promotes CD34+ cell migration via a MMP-2-dependent mechanism. (2012) Stem Cells Dev, 21:3162-3172 (IF2012=4,670)

Ben Azouna N, Jenhani F, Regaya Z, Berrais L, Ben Othman T, Ducroq E, Domenech J. (2012) Phenotypical and functional characteristics of mesenchymal stem cells from bone marrow: comparison of culture using different media supplemented with human platelet lysate or fetal bovine serum. Stem Cell Res Ther, 3:6 (IF2012=3,652)

Trost M, Sauvageau M, Herault O, Deleris P, Chagraoui J, Mayotte N, Meloche S, Sauvageau G, Thibault P. (2012) Comparative phosphoproteome analysis of stem cell leukemias reveals differential cytoplasmic translocation of PRC2 polycomb proteins. Blood, 120:e17-27 (IF2012=9,060)

Bire S, Rouleux-Bonnin F. (2012) Transposable elements as tools for reshaping the genome: it is a huge world after all! Methods Mol Biol, 859:1-28 (revue)

Varon C, Dubus P, Mazurier F, Asencio C, Chambonnier L, Ferrand J, Giese A, Senant-Dugot N, Carlotti M, Mégraud F. (2012) Helicobacter pylori infection recruits bone marrow-derived cells that participate in gastric preneoplasia in mice. Gastroenterology, 142:281-291 (IF2012=12,821)

Cholez E, Debuysscher V, Bourgeais J, Boudot C, Leprince J, Tron F, Brassart B, Regnier A, Bissac E, Pecnard E, Gouilleux F, Lassoued K, Gouilleux-Gruart V. (2012) Evidence for a protective role of the STAT5 transcription factor against oxidative stress in human leukemic pre-B cells. Leukemia 2012, 26:2390-2397 (IF2012=10,164)

Willems L, Chapuis N, Puissant A, Maciel TT, Green AS, Jacque N, Vignon C, Park S, Guichard S, Herault O, Fricot A, Hermine O, Moura IC, Auberger P, Ifrah N, Dreyfus F, Bonnet D, Lacombe C, Mayeux P, Bouscary D, Tamburini J. (2012) The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia. Leukemia, 26:1195-1202 (IF2012=10,164)

Damm F, Kosmider O, Gelsi-Boyer V, Renneville A, Carbuccia N, Hidalgo-Curtis C, Della Valle V, Couronné L, Scourzic L, Chesnais V, Guerci-Bresler A, Slama B, Beyne-Rauzy O, Schmidt-Tanguy A, Stamatoullas-Bastard A, Dreyfus F, Prébet T, de Botton S, Vey N, Morgan MA, Cross NC, Preudhomme C, Birnbaum D, Bernard OA, Fontenay M; Groupe Francophone des Myélodysplasies. (2012) Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes. Blood, 119:3211-3218 (IF2012=9,060)

Frisan E, Vandekerckhove J, de Thonel A, Pierre-Eugène C, Sternberg A, Arlet JB, Floquet C, Gyan E, Kosmider O, Dreyfus F, Gabet AS, Courtois G, Vyas P, Ribeil JA, Zermati Y, Lacombe C, Mayeux P, Solary E, Garrido C, Hermine O, Fontenay M. (2012) Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes. Blood, 119:1532-1542 (IF2012=9,060) 

Gonzalez-Aguilar A, Idbaih A, Boisselier B, Habbita N, Rossetto M, Laurenge A, Bruno A, Jouvet A, Polivka M, Adam C, Figarella-Branger D, Miquel C, Vital A, Ghesquières H, Gressin R, Delwail V, Taillandier L, Chinot O, Soubeyran P, Gyan E, Choquet S, Houillier C, Soussain C, Tanguy ML, Marie Y, Mokhtari K, Hoang-Xuan K. (2012) Recurrent Mutations of MYD88 and TBL1XR1 in Primary Central Nervous System Lymphomas. Clin Cancer Res 18:5203-5211 (IF2012=7,837)

Ponciano A, de Muret A, Machet L, Gyan E, du Sorbier CM, Molinier-Frenkel V, Gaulard P, Ortonne N. (2012) Epidermotropic secondary cutaneous involvement by relapsed angioimmunoblastic T-cell lymphoma mimicking mycosis fungoides: a case report. J Cutan Pathol 39:1119-1124 (IF 2012=1,766)

Renner C, Zinzani P, Gressin R, Klingbiel D, Dietrich PY, Hitz F, Bargetzi M, Mingrone W, Martinelli G, Trojan A, Bouabdallah K, Lohri A, Gyan E, Biaggi C, Cogliatti S, Bertoni F, Ghielmini M, Brauchli P, Ketterer N. (2012) A multicenter phase II trial (SAKK 36/06) of single-agent Everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma. Haematologica, 97:1085-1091 (IF2012=5,935)

Chaussade H, Bastides F, Lissandre S, Blouin P, Bailly E, Chandenier J, Gyan E, Bernard L. (2012) Usefulness of corticosteroid therapy during chronic disseminated candidiasis: case reports and literature review. J Antimicrob Chemother, 67:1493-1495 (IF2012=5,338)

2011

Palazzoli F, Bire S, Bigot Y, Bonnin-Rouleux F. (2011) Landscape of chromatin control element patents: positioning effects in pharmaceutical bioproduction. Nat Biotechnol, 29:593-597 (IF2011=23,268)


Rezvani HR, Kim AL, Rossignol R, Ali N, Daly M, Mahfouf W, Bellance N, Taïeb A, de Verneuil H, Bickers DR, Mazurier F. (2011) XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas. J Clin Invest, 12&:195-211 (IF2011=13,069)


Rezvani HR, Ali N, Nissen LJ, Harfouche G, de Verneuil H, Taïeb A, Mazurier F. (2011) HIF-1α in epidermis: oxygen sensing, cutaneous angiogenesis, cancer, and non-cancer disorders. J Invest Dermatol, 131:1793-1805 (IF2011=6,314)


Rezvani HR, Ali N, Serrano-Sanchez M, Dubus P, Varon C, Ged C, Pain C, Cario-André M, Seneschal J, Taïeb A, de Verneuil H, Mazurier F. (2011) Loss of epidermal hypoxia-inducible factor-1α accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci, 124:4172-4183 (IF 2011=6,111)


Dhennin-Duthille I, Nyga R, Yahiaoui S, Gouilleux-Gruart V, Regnier A, Lassoued K, Gouilleux F. (2011) The tumor suppressor hTid1 inhibits STAT5b activity via functional interaction. J Biol Chem, 286:5034-5042 (IF2011=4,773)


Rezvani HR, Rossignol R, Ali N, Benard G, Tang X, Yang HS, Jouary T, de Verneuil H, Taïeb A, Kim AL, Mazurier F. (2011) XPC silencing in normal human keratinocytes triggers metabolic alterations through NOX-1 activation-mediated reactive oxygen species. Biochim Biophys Acta, 1807:609-619 (IF2011=4,843)


Jenhani F, Durand V, Ben Azouna N, Thallet S, Ben Othmen T, Bejaoui M, Domenech J. (2011) Human cytokine expression profile in various conditioned media for in vitro expansion bone marrow and umbilical cord blood immunophenotyped mesenchymal stem cells. Transplant Proc, 43:639-643 (IF2011=1,005)


Friedbichler K, Hoelbl A, Li G, Bunting KD, Sexl V, Gouilleux F, Moriggl R. (2011) Serine phosphorylation of the Stat5a C-terminus is a driving force for transformation. Front Biosci, 17:3043-3056 (IF2011=3,520)

Ivanovic Z, Duchez P, Chevaleyre J, Vlaski M, Lafarge X, Dazey B, Robert-Richard E, Mazurier F, Boiron JM. (2011) Clinical-scale cultures of cord blood CD34(+) cells to amplify committed progenitors and maintain stem cell activity. Cell Transplant, 20:1453-1463

Belmokhtar K, Bourguignon T, Worou ME, Khamis G, Bonnet P, Domenech J, Eder V. (2011) Regeneration of three layers vascular wall by using BMP2-treated MSC involving HIF-1α and Id1 expressions through JAK/STAT pathways. Stem Cell Rev, 7:847-859 (IF2011=3,739)

Ben Nasr M, Reguaya Z, Berraies L, Maamar M, Ladeb S, Ben Othmen T, Mellouli F, Béjaoui M, Domenech J, Jenhani F. (2011) Association of stromal cell-derived factor-1-3'A polymorphism to higher mobilization of hematopoietic stem cells CD34+ in Tunisian population. Transplant Proc, 43:635-638 (IF2011=1,005)

Monjanel H, Deconinck E, Perrodeau E, Gastinne T, Delwail V, Moreau A, François S, Berthou C, Gyan E, Milpied N, on behalf of the GOELAMS. (2011) Long-Term Follow-up of Tandem High-Dose Therapy with Autologous Stem Cell Support for Adults with High-Risk Age-Adjusted International Prognostic Index Aggressive non-Hodgkin's Lymphomas: a GOELAMS Pilot Study. Biol Blood Marrow Transplant, 17:935-940 (IF2011=3,873)

Khellaf M, Michel M, Quittet P, Viallard JF, Alexis M, Roudot-Thoraval F, Cheze S, Durand JM, Lefrère F, Galicier L, Lambotte O, Panelatti G, Slama B, Damaj G, Sebahoun G, Gyan E, Delbrel X, Dhedin N, Royer B, Schleinitz N, Rossi JF, Mahévas M, Languille L, Bierling P, Godeau B. (2011) Romiplostim safety and efficacy for immune thrombocytopenia in clinical practice: 2-year results of 72 adults in a romiplostim compassionate-use program. Blood, 118:4338-4345 (IF2011=9,898)

Trotman J, Fournier M, Lamy T, Seymour JF, Sonet A, Janikova A, Shpilberg O, Gyan E, Tilly H, Estell J, Forsyth C, Decaudin D, Fabiani B, Gabarre J, Salles B, Van Den Neste E, Canioni D, Garin E, Fulham M, Vander Borght T, Salles G. (2011) Positron emission tomography-computed tomography (PET-CT) after induction therapy is highly predictive of patient outcome in follicular lymphoma: analysis of PET-CT in a subset of PRIMA trial participants. J Clin Oncol, 29:3194-200 (IF2011=18,372)


Le Gouill S, De Guibert S, Planche L, Brice P, Dupuis J, Cartron G, Van Hoof A, Casasnovas O, Gyan E, Tilly H, Fruchart C, Deconinck E, Fitoussi O, Gastaud L, Delwail V, Gabarre J, Gressin R, Blanc M, Foussard C, Salles G; GELA and GOELAMS. (2011) Impact of the use of autologous stem cell transplantation at first relapse both in naive and previously rituximab exposed follicular lymphoma patients treated in the GELA/GOELAMS FL2000 study. Haematologica, 96:1128-1135 (IF2011=6,424)


2010

Rezvani HR, Mahfouf W, Ali N, Chemin C, Ged C, Kim AL, de Verneuil H, Taïeb A, Bickers DR, Mazurier F. (2010) Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes. Nucleic Acids Res, 38:797-809 (IF2010=7,836)

Chapuis N, Tamburini J, Green AS, Vignon C, Bardet V, Neyret A, Pannetier M, Willems L, Park S, Macone A, Maira SM, Ifrah N, Dreyfus F, Herault O, Lacombe C, Mayeux P, Bouscary D. (2010) Dual inhibition of PI3K and mTORC1/2 signalling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia. Clin Cancer Res, 16:5424-5435 (IF2010=7,338)

Robert-Richard E, Lalanne M, Lamrissi-Garcia I, Guyonnet-Duperat V, Richard E, Pitard V, Mazurier F, Moreau-Gaudry F, Ged C, de Verneuil H. (2010) Modeling of congenital erythropoietic porphyria by RNA interference: a new tool for preclinical gene therapy evaluation. J Gene Med, 12:637-646

Friedbichler K, Kerenyi MA, Kovacic B, Li G, Hoelbl A, Yahiaoui S, Sexl V, Müllner EW, Fajmann S, Cerny-Reiterer S, Valent P, Beug H, Gouilleux F, Bunting KD, Moriggl R. (2010) Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood, 116:1548-1558 (IF2010=10,558)

Dedieu S, Canron X, Rezvani HR, Bouchecareilh M, Mazurier F, Sinisi R, Zanda M, Moenner M, Bikfalvi A, North S. (2010) The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A. BMC Med, 8:19 (IF2010=5,750)

Li G, Miskimen KL, Wang Z, Yan Xie X, Tse W, Gouilleux F, Moriggl R,  Bunting KD. (2010) Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin. Leukemia, 4:1397-1405 (IF2010=8,966)

Amara S, Domenech J, Jenhani F. (2010) Stromal cell-derived factor 1 polymorphism in patients infected with HIV and implications for AIDS progression in Tunisia. HIV AIDS, 2:203-209

Boudot C, Saidak Z, Boulanouar AK, Petit L, Gouilleux F, Massy Z, Brazier M, Mentaverri R, Kamel S. (2010) Implication of the calcium sensing receptor and the Phosphoinositide 3-kinase/Akt pathway in the extracellular calcium-mediated migration of RAW 264.7 osteoclast precursor cells. Bone, 46 :1416-1423 (IF2010=4,601)

Kelaidi C, Stamatoullas A, Beyne-Rauzy O, Raffoux E, Quesnel B, Guerci A, Dreyfus F, Brechignac S, Berthou C, Prebet T, Hicheri Y, Hacini M, Delaunay J, Gourin MP, Camo JM, Zerazhi H, Taksin AL, Legros L, Choufi B, Fenaux P; Groupe Francophone des Myélodysplasies. (2010) Daily practice management of myelodysplastic syndromes in France: data from 907 patients in a one-week cross-sectional study by the Groupe Francophone des Myelodysplasies. Haematologica, 95:892-899 (IF2010=6,532)

Gressin R, Caulet-Maugendre S, Deconinck E, Tournilhac O, Gyan E, Moles MP, El Yamani A, Cornillon J, Rossi JF, Le Gouill S, Lepeu G, Damaj G, Solal Celigny P, Maisonneuve H, Corront B, Vilque JP, Casassus P, Lamy-de-La-Chapelle T, Colonna M, Colombat P; for the French GOELAMS group. (2010) Evaluation of the (R)VAD+C regimen for the treatment of newly diagnosed Mantle Cell Lymphoma. Combined results of two prospective phase II trials from the French GOELAMS group. Haematologica, 95:1350-1357 (IF2010=6,532)


2009
Casteret S, Chbab N, Cambefort J, Augé-Gouillou C, Bigot Y, Rouleux-Bonnin F. (2009) Physical properties of DNA components affecting the transposition efficiency of the mariner Mos1 element. Mol Genet Genomics, 282:531-546 (IF2009=2,579)

Baumgartner C, Cerny-Reiterer S, Sonneck K, Mayerhofer M, Gleixner KV, Fritz R, Kerenyi M, Boudot C, Gouilleux F, Kornfeld JW, Sillaber C, Moriggl R, Valent P. (2009) Expression of Activated STAT5 in Neoplastic Mast Cells in Systemic Mastocytosis. Subcellular Distribution and Role of the Transforming Oncoprotein KIT D816V. Am J Pathol, 175:2416-2429 (IF2009=5,673)

El Hiani Y, Ahidouch A, Lehen'kyi V, Hague F, Gouilleux F, Mentaverri R, Kamel S, Lassoued K, Brûlé G, Ouadid-Ahidouch H. (2009) Extracellular signal-regulated kinases 1 and 2 and TRPC1 channels are required for calcium-sensing receptor-stimulated MCF-7 breast cancer cell proliferation. Cell Physiol Biochem, 23:335-346 (IF2009=3,563)

Coipeau P, Rosset P, Langonné A, Gaillard J , Delorme B, Rico A, Domenech J, Charbord P, Sensebé S. (2009) Impaired differentiation potential of human trabecular bone mesenchymal stromal cells from elderly patients. Cytotherapy, 11:584-594 (IF2009=2,204)

Gyan E, Foussard C, Bertrand P, Michenet P, Le Gouill S, Berthou C, Maisonneuve H, Delwail V, Gressin R, Quittet P, Vilque JP, Desablens B, Jaubert J, Ramée JF, Arakelyan N, Thyss A, Moluçon-Chabrot C, Delépine R, Milpied N, Colombat P, Deconinck E; Groupe Ouest-Est des Leucémies et des Autres Maladies du Sang (GOELAMS). (2009) High-dose therapy followed by autologous purged stem cell transplantation and doxorubicin-based chemotherapy in patients with advanced follicular lymphoma: a randomized multicenter study by the GOELAMS with final results after a median follow-up of 9 years. Blood, 113:995-1001 (IF2009=10,555)

 

2008

Harir N, Boudot C, Friedbichler K, Sonneck K, Kondo R, Martin-Lannerée S, Kenner L, Kerenyi M, Yahiaoui S, Gouilleux-Gruart V, Gondry J, Bénit L, Dusanter-Fourt I, Lassoued K, Valent P, Moriggl R, Gouilleux F. (2008) Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI 3-kinase signaling cascade. Blood, 112:2463-2473 (IF2008=10,432)

Fontenay M, Gyan E. (2008) Apoptotic pathways to death in myelodysplastic syndromes. Haematologica, 93 :1288-1292 (IF2008=5,978)

Gyan E, Frisan E, Beyne-Rauzy O, Deschemin JC, Pierre-Eugene C, Randriamampita C, Dubart-Kupperschmitt A, Garrido C, Dreyfus F, Mayeux P, Lacombe C, Solary E, Fontenay M. (2008) Spontaneous and Fas-induced apoptosis of low-grade MDS erythroid precursors involves the endoplasmic reticulum. Leukemia, 22:1864-1873 (IF2008=8,634)

Bonnet P, Awede B, Rochefort GY, Mirza A, Lermusiaux P, Domenech J, Eder V. (2008) Electrophysiological maturation of rat mesenchymal stem cells after induction of vascular smooth muscle cell differentiation in vitro. Stem Cells Dev, 17 :1131-1140 (IF2008=3,273)

James C, Mazurier F, Dupont S, Chaligne R, Lamrissi-Garcia I, Tulliez M, Lippert E, Mahon FX, Pasquet JM, Etienne G, Delhommeau F, Giraudier S, Vainchenker W, de Verneuil H. The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity. Blood, 112:2429-2438 (IF2008=10,432)

Mirza A, Hyvelin JM, Rochefort GY, Lermusiaux P, Antier D, Awede B, Bonnet P, Domenech J, Eder V. (2008) Undifferentiated mesenchymal stem cells seeded on a vascular prosthesis contribute to the restoration of a physiologic vascular wall. J Vasc Surg, 47 :1313-1321 (IF2008=3,770)

Sinzelle L, Jégot G, Brillet B, Rouleux-Bonnin F, Bigot Y, Augé-Gouillou C. (2008) Factors acting on Mos1 transposition efficiency. BMC Mol Biol, 26:106 (IF2008=2,810)

Kornfeld JW, Grebien F, Kerenyi MA, Friedbichler K, Kovacic B, Zankl B, Hoelbl A, Nivarti H, Beug H, Sexl V, Muller M, Kenner L, Mullner EW, Gouilleux F, Moriggl R. (2008) The different functions of Stat5 and chromatin alteration through Stat5 proteins. Front BioSci, 13:6237-6254 (IF2008=3,308)

Blasco H, Silly S, Tournamille JF, Gyan E, Sénécal D, André V, Colombat P, Le Guellec C. (2008) The need for a better definition of therapeutic indications of carboxypeptidase in delayed elimination of methotrexate. Therapie, 63:19-28 (IF2008=0,445)

 

2007

Gallay N, Anani L, Lopez A, Colombat P, Binet C, Domenech J, Weksler BB, Malavasi F, Herault O. (2007) The role of CD31/PECAM-1 and CD38 antigens in marrow microenvironmental retention of acute myeloid leukemia cells. Cancer Res, 6:8624-8632 (IF2007=7,672)

Harir N, Pecquet C, Kerenyi C,  Sonneck K, Kovacic B, Nyga R,  Brevet M,  Dhennin I,  Gouilleux-Gruart V, Beug H, Valent P,  Lassoued K,  Moriggl R,  Gouilleux F. (2007) Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI 3-kinase in myeloid leukemias. Blood, 109:1678-1686 (IF2007=10,896)

López Ponte A, Marais E, Gallay N, Langonné A, Delorme B, Herault O, Charbord P, Domenech J. (2007) The in vitro migration capacity of human bone marrow mesenchymal stem cells: Comparison of chemokine and growth factor chemotactic activities. Stem Cells, 25:1737-1745 (IF2007=7,531)

Rezvani HR, Dedieu S, North S, Belloc F, Rossignol R, Letellier T, de Verneuil H, Taïeb A, Mazurier F. (2007) Hypoxia-inducible factor-1alpha, a key factor in the keratinocyte response to UVB exposure. J Biol Chem, 282:16413-16422 (IF2007=5,581)

Pecquet C, Nyga R, Penard-Lacronique V, Smithgall TE, Murakami H , Régnier A , Lassoued, Gouilleux F. (2007) The Src tyrosine kinase Hck is required for Tel-Abl- but not for Tel-Jak2-induced cell transformation. Oncogene, 26:1577-1585 (IF2007=6,440)

Regina S, Herault O, D'Alteroche L, Binet C, Gruel Y. (2007) JAK2 V617F is specifically associated with idiopathic splanchnic vein thrombosis. J Thromb Haemost, 5:859-861 (IF2007=5,947)

Chaligné R, James C, Tonetti C, Besancenot R, Le Couédic JP, Fava F, Mazurier F, Godin I, Maloum K, Larbret F, Lécluse Y, Vainchenker W, Giraudier S. (2007) Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis. Blood, 110:3735-3743 (IF2007=10,896)

Petit A, Rouleux-Bonnin F, Lambelé M, Pollet N, Bigot Y. (2007) Properties of the various Botmar1 transcripts in imagoes of the bumble bee, Bombus terrestris (Hymenoptera: Apidae). Gene, 390:52-66 (IF2007=2,871)

Haond C, Farace F, Guillier M, Lécluse Y, Mazurier F, Vainchenker W, Turhan AG. (2007) Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle. Cell Res, 17:783-791 (IF2007=4,217)

Rébé C, Cathelin S, Launay S, Filomenko R, Prévotat L, L'Ollivier C, Gyan E, Micheau O, Grant S, Dubart-Kupperschmitt A, Fontenay M, Solary E. (2007) Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation. Blood, 109:1442-1450 (IF2007=10,896)

Di Scala E, Rose S, Herault O, Argibay J, Cosnay P, Bozon V. (2007) Conformational state of human cardiac 5-HT(4(g)) receptors influences the functional effects of polyclonal anti-5-HT(4) receptor antibodies. Biochem Pharmacol, 73:964-971 (IF2007=4,001)

Moreau P, Voillat L, Benboukher L, Mathiot C, Dumontet C, Robillard N, Herault O, Garnache F, Garand R, Varoqueaux N, Avet-Loiseau H, Harousseau JL, Bataille R; IFM group. (2007) Rituximab in CD20 positive multiple myeloma. Leukemia, 21:835-836 (IF2007=6,924)

Petit A, Rouleux-Bonnin F, Lambelé M, Pollet N, Bigot Y. (2007) Properties of the various Botmar1 transcripts in imagoes of the bumble bee, Bombus terrestris (Hymenoptera: Apidae). Gene 390:52-66 (IF2007=2,871)

Borowiec AS, Hague F, Harir N, Guérineau F, Gouilleux F, Lassoued K, Ouadid-Ahidouch H. (2007) IGF-1 activates hEAG K+ channels through a PI3 kinase-dependent signalling pathway in breast cancer cells. J Cell Physiol, 212:690-701 (IF2007=3,643)

Guillard J, Decrop M, Gallay N, Espanel C, Boissier E, Herault O, Viaud-Massuard MC. (2007) Synthesis and biological evaluation of 7-azaindole derivatives, synthetic cytokinin analogues. Bioorg Med Chem Lett, 17:1934-1937 (IF2007=2,262)

Fermé C, Eghbali H, Meerwaldt JH, Rieux C, Bosq J, Berger F, Girinsky T, Brice P, van't Veer MB, Walewski JA, Lederlin P, Tirelli U, Carde P, Van den Neste  E, Gyan E, Monconduit M, Diviné M, Raemaekers JM, Salles G, Noordijk EM, Creemers GJ, Gabarre J, Hagenbeek A, Reman O, Blanc M, Thomas J, Vié B, Kluin-Nelemans JC, Viseu F, Baars JW, Poortmans P, Lugtenburg PJ, Carrie C, Jaubert J, Henry-Amar M; EORTC-GELA H8 Trial. (2007) Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease. N Engl J Med, 357:1916-1927 (IF2007=52,589)

Hunault M, Truchan-Graczyk M, Caillot D, Harousseau JL, Bologna S, Himberlin C, Guyotat D, Berthou C, Casassus P, Baranger L, Béné MC, Ifrah N, Gyan E; GOELAMS Group. (2007) Outcome of adult T-lymphoblastic lymphoma after acute lymphoblastic leukemia-type treatment: a GOELAMS trial. Haematologica, 92:1623-1630 (IF2007=5,516)

Espanel C, Kafando E, Hérault B, Petit A, Herault O, Binet C. (2007) [Iron deficiency anaemia: clinical presentation, biological diagnosis and management]. Transfus Clin Biol, 14:21-24 (IF2007=1,138)


2006

Dommange F, Cartron G, Espanel C, Gallay N, Domenech J, Benboubker L, Ohresser M, Colombat P, Binet C, Watier H, Herault O. (2006) CXCL12 polymorphism and malignant cell dissemination / tissue infiltration in acute myeloid leukemia. FASEB J, 20:1913-1915 (IF2006=6,721)

Rochefort GY, Delorme B, Lopez A, Herault O, Bonnet P, Charbord P, Eder V, Domenech J. (2006) Multipotential mesenchymal stem cells are mobilized into peripheral blood by hypoxia. Stem Cells, 24:2202-2208 (IF2006=7,924)

Gyan E, Porteu F, Fontenay M. (2006) Reply to « hRap1B-retro: a novel human processed Rap1B gene blurs the picture ? » by Zemojtel et al. Leukemia, 20:146-147 (IF2006=6,146)

Bideshi DK, Demattei MV, Rouleux-Bonnin F, Stasiak K, Tan Y, Bigot S, Bigot Y, Federici BA. (2006) Genomic sequence of Spodoptera frugiperda Ascovirus 1a, an enveloped, double-stranded DNA insect virus that manipulates apoptosis for viral reproduction. J Virol, 80:11791-11805

Fontenay M, Cathelin S, Amiot M, Gyan E, Solary E. (2006) Mitochondria in hematopoiesis and hematological diseases. Oncogene, 25:4757-4767 (IF2006=6,582)

Bideshi DK, Demattei MV, Rouleux-Bonnin F, Stasiak K, Tan Y, Bigot S, Bigot Y, Federici BA. (2006) Genomic sequence of Spodoptera frugiperda Ascovirus 1a, an enveloped, double-stranded DNA insect virus that manipulates apoptosis for viral reproduction. J Virol 80:11791-11805 (IF2006=5,341)

Maillard S, Gauduchon J, Marsaud V, Gouilleux F, Connault E, Opolon P, Fattal E, Sola B, Renoir JM. (2006) Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma. J Steroid Biochem Mol Biol, 100:67-78 (IF2006=2,825)