Brevets et méthodes

Bourgeais J, Herault O. (2021) In vitro analysis of energy metabolism in bone-marrow mesenchymal stromal cells. Methods Mol Biol, accepted

Ravalet N,* Foucault A,* Picou F,* Gombert M, Renoult E, Lejeune J, Vallet N, Lachot S, Rault E, Gyan E, Bene MC,  Herault O. (2021) Automated early detection of myelodysplastic syndrome within the general population using the research parameters of Beckman-Coulter DxH 800 hematology analyzer. Cancers (Basel), 13:389 *equal contributors

Herault O, Sire O - "Méthode pronostic d’hémopathies" (Détection et suivi des myélodysplasies en 2 minutes sur une goutte de plasma sanguin par spectroscopie moyen infra-rouge). Brevet N° FR2005494 du 25/05/2020

Coste E, Rouleux-Bonnin F. (2020) The crucial choice of reference genes: identification of miR-191-5p for normalization of miRNAs expression in bone marrow mesenchymal stromal cell and HS27a/HS5 cell lines. Sci Rep 10:17728. doi: 10.1038/s41598-020-74685-7

Lanznaster D, Bourgeais J, Bruno C, Hergesheimer RC, Thepault R-A, Vourc’h P, Corcia P, Andres CR, Herault O*, Blasco H*. (2019) TDP-43-mediated toxicity in HEK293T cells: a fast and reproducible protocol to be employed in the search of new therapeutic options against amyotrophic lateral sclerosis. Cells, 2019 Dec 26;9(1). pii: E68. doi: 10.3390/cells9010068, *equal contributors

Nehme A, Awada Z, Kobeissy F, Mazurier F, Zibara K. (2018) Coupling large-scale omics data for deciphering systems complexity. In: Rajewsky N., Jurga S., Barciszewski J. (eds) Systems Biology. RNA Technologies. Springer, Cham

Bire S, Ishac N, Rouleux-Bonnin F. (2016) In vitro synthesis, delivery, and bioavailability of exogenous mRNA in gene transfer mediated by PiggyBac transposition. Methods Mol Biol, 1428:187-217

Bastie C, Rouleux-Bonnin F. DNA Elements Tetris: A strategy for gene correction.  In: Modern Tools for Genetic Engineering. Edited by Michael S.D. Kormann. InTech, Rijeka, Croatia, 2016

Herault O. (2015) « Hemopathy prognosis method » - Brevet WO2016083742 du 26/11/2015

Vignon C, Debeissat C, Georget MT, Bouscary D, Gyan E, Rosset P, Herault O.  (2013) Flow cytometric quantification of all phases of the cell cycle and apoptosis in a two-color fluorescence plot. PLOS One, 8:e68425 (IF2012=3,730)

Bire S, Ley D, Casteret S, Mermod N, Bigot Y, Rouleux-Bonnin F. (2013) Optimization of the piggyBac transposon using mRNA and insulators: Toward a more reliable gene delivery system. PLoS One, 8:e82559 (IF2012=3,730)

Bire S, Gosset D, Jégot G, Midoux P, Pichon C, Rouleux-Bonnin F. (2013) Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition. BMC Biotechnol, 13:75 (IF2012=2,165)

Respaud R, Quenuma L,  Plichon C, Tournamille JF, Gyan E, Antier D, Viaud-Massuard MC. (2013) A stability-indicating, ion-pairing, reversed-phase liquid chromatography method for studies of daunorubicin degradation in i.v. infusion fluids. J Pharm Biomed Anal, 83:164–170 (IF2011=2,967)

Herault O
, Vignon C. (2012) « Method for diagnosing hematological disorders » – Brevet WO2012085188 A1 du 22/06/2011
(caractérisation à visée diagnostique de l’expression des gènes antioxydants,  signature antioxydante dans les hémopathies ou « antioxydogramme »)

Palazzoli F, Bire S, Bigot Y, Bonnin-Rouleux F. (2011) Landscape of chromatin control element patents: positioning effects in pharmaceutical bioproduction. Nat Biotechnol, 29:593-597

Herault O, Binet C, Rico A, Degenne M, Bernard MC, Chassaigne M, Sensebe L.(2001) Evaluation of performance of white blood cell reduction filters: an original flow cytometric method for detection and quantification of cell-derived membrane fragments. Cytometry, 45:277-284

Herault O, Colombat P, Domenech J, Degenne M, Bremond JL, Sensebe L, Bernard MC, Binet C. (1999) A rapid single-laser flow cytometric method for discrimination of early apoptotic cells in a heterogenous cell population. Br J Haematol, 104:530-537